List of Previous Teleseminars

Previous DRSG Seminars – 2000-2017

Considerations for the Dose‐Response Analyses of Inorganic Arsenic Health Outcomes
Jeff Gift, U.S. EPA
3 October 2017
Recordings: Recording (49 MB); Audio Only (22 MB).

Understanding the Biochemical Origin of Sigmoidal Dose Responses: Ultrasensitive Response Motifs
Qiang Zhang, Emory University
5 September 2017
Recordings: Recording (80 MB); Audio Only (27 MB).

Using 21st Century Science for Risk-related evaluations: An Overview of the NAS Risk21 Report
Jonathan Samet, George Daston, & Lauren Zeise, On behalf of the National Academies Risk21 Committee
1 August 2017

Exposure‐Response in Environmental Toxicology and Risk Assessment, from Receptors to Ecological Landscapes
Wayne G. Landis, Western Washington University
2 May 2017

Health and Economic Consequences of Endocrine Disruptors in the US and EU
Leo Transande, New York University
4 April 2017

Facilitated Discussion: Mentoring in Risk Assessmenr
2 February 2017

Strengthening human health risk assessment of chemicals by integration of toxicogenomics data
Julie Bourdon-Lacombe,, Health Canada
4 October 2016

Bayesian dose-response analysis for re-assessment of arsenic-tumor data
Lyle D. Burgoon, U.S. Army Engineer Research and Development Center
6 September 2016

Statistical strategy for determining sufficient similarity of complex mixtures: A case study of ginkgo biloba extract
Chris Gennings, Icahn School of Medicine at Mount Sinai
2 August 2016

Potency of opportunistic pathogens in water systems
Jade Mitchell, Michigan State University
5 July 2016

Complete protection against aflatoxin B1-induced liver cancer with a triterpenoid: DNA adduct dosimetry and genotoxicity threshold
Bill D. Roebuck, The Geisel School of Medicine at Dartmouth
5 April 2016

Modeling U-shaped exposure-response relationships for agents that demonstrate toxicity due to both excess and deficiency
Daniel Krewski, University of Ottawa
6 October 2015

Perinatal stress and early childhood respiratory disorders: dose-response and sex-specific effects
Rosalind Wright, Mount Sinai Hospital
1 September 2015

What would Willie Sutton say about dose response analysis for unconventional gas drilling?
Bernard Goldstein, (Emeritus) University of Pittsburgh Schools of the Health Sciences
7 July 2015

Risk Analysis – Visions for the Future
Dale Hattis, Clark University
2 June 2015

The Interaction Between Chemical and Physical Agents: The Example of Ototoxicants and Noise
Thais C. Morata, NIOSH National Occupational Research Agenda Manufacturing Sector Council
7 October 2014

Application of the WHO Framework for Combined Exposures: Implications for Assessment
Bette Meek, Institute of Population Health, University of Ottawa
2 September 2014

NCTR/FDA Research on BPA: Integrating Pharmacokinetics in Animal Models and Humans, Rat Toxicology Studies, Human Biomonitoring, and PBPK Modeling into Risk Assessment
Daniel Doerge, National Center for Toxicological Research, FDA
5 August 2014

Mixtures Research at the National Institute of Environmental Health Sciences (NIEHS)
Cynthia Rider, National Toxicology Program, NIEHS
6 May 2014

U.S. EPA State of the Science Evaluation: Nonmonotonic Dose Responses as They Apply to Estrogen, Androgen, and Thyroid Pathways and EPA Testing and Assessment Procedures
Rita Schoeny, USEPA Office of Science Policy
1 October 2013

The Non-Linear Nasal Carcinogen Vinyl Acetate and Some Challenges of Tox21 for Non-Linear Dose-Response Assessment
Justin Teeguarden, Pacific Northwest National Laboratory
10 September 2013

Model Averaged Benchmark Dose Estimations—From Research to Practice
Kan Shao, USEPA National Center for Environmental Assessment
6 August 2013

State-of-the-Science: Inhalation Gas Dosimetry and Risk Assessment
John Stanek, USEPA National Center for Environmental Assessment
2 April 2013

Improving Risk Assessment for Mixtures Using Dose-Dependent Responses
Resha Putzrath, Navy and Marine Corps Public Health Center
4 September 2012

Evaluating the Plausibility of Estrogen Receptors as Mediators of BPA Toxicity in the Context of Human Serum Concentrations of Unconjugated BPA
Justin Teeguarden, Pacific Northwest National Laboratory
4 June 2012

Bisphenol A: Evaluating Toxicity and Dose Response in Rodent Models
Barry Delclos, U.S. FDA
3 April 2012

Computational Toxicology and High-Throughput Risk Assessment
Richard Judson, U.S. EPA
6 September 2011

Integration of Dosimetry, Human Exposure and High-Throughput Screening Data in the Toxicity Assessment of Environmental Chemicals
Barbara Wetmore, Hamner Institutes for Health Sciences
June 7, 2011

NexGen Risk Assessments: Challenges and Opportunities for Dose-Response Assessment
Weihsueh Chiu, U.S. EPA
12 April 2011

The Use and Misuse of Dose Thresholds in Risk Assessment
Kenny Crump, Louisiana Tech University
7 September 2010

Microbial Dose-Response & Its Use in Estimating the Benefits of EPA’s Drinking Water Rules
Jeff Swartout, U.S. EPA National Center for Environmental Assessment
Mike Messner, U.S. EPA Office of Ground Water and Drinking Water
Stig Regli, U.S. EPA Office of Ground Water and Drinking Water
3 August 2010

Threshold of Toxicological Concern (TTC)
Michael Laufersweiler, Procter & Gamble Central Product Safety, and
Stephen Olin, ILSI Research Foundation
3 March 2010

High Throughput Screening for Hazard and Risk of Environmental Contaminants
David J. Dix, U.S. EPA
6 October 2009

Using Empirical Data on Toxicity Pathways in the Prediction of Responses at Low Doses
Paul Price, Dow Chemical Company
1 September 2009

Chemical-Specific Adjustment Factors: The IPCS Approach to Developing Non-Default Values for Inter and Intra-species Extrapolation
John Lipscomb, U.S. EPA
Categorical Regression Modeling of Multiple Effects from Chemical Mixture Exposures in Cumulative Risk Assessment
Linda Teuschler, U.S. EPA
9 June 2009

Discussion of National Academy of Sciences Report - Science and Decisions: Advancing Risk Assessment
Michael Dourson, TERA
3 March 2009

The BMD Approach in Europe: Recent Developments in Acceptance, and Some Specific Views
Wout Slob, RIVM
2 September 2008

Dose-Response Analysis in Environmental Risk Assessment:
Where Are We, and Where Are We Going?
Weihsueh Chiu, U.S. EPA
3 June 2008

Characterizing Dose-Response Model Uncertainty Using Model Averaging
Matthew Wheeler, NIOSH
5 March 2008

Radiation Cancer Risk Estimates and the Use of the Linear Nonthreshold Model
Julian Preston, U.S. EPA
11 September 2007

Toxicokinetics and Risk Assessment, a text
John Lipscomb, U.S. EPA
5 June 2007

PBPK Modeling for Acrylamide: Relating Mechanisms, Adducts, Metabolites, and Kinetics to Risk Assessment
Daniel R. Doerge; John F. Young, NCTR, U.S. FDA
6 March 2007

Intraspecies Variability in Toxicant Effects: Nuisance, Nemesis or Sustenance for Risk Assessment?
Robert MacPhail, U.S. EPA
5 September 2006

Mode of Action in Assessing the Human Relevance of Animal Tumors: An EPA Perspective
Vicki Dellarco; Anna Lowit, U.S. EPA
6 February 2006

Inhalation Toxicity of Single Wall Carbon Nanotubes
Robert R. Mercer, NIOSH Unique Properties of Nanomaterials that Raise Concerns for Toxicology Research
Jo Anne Shatkin, The Cadmus Group
6 June 2006

Computational Systems Biology and Dose Response Assessment
Mel Andersen, CIIT Centers for Health Research
6 September 2005

Age-Related Differences in Susceptibility to Carcinogenesis—Human Risk Inferences from an Analysis of Animal Bioassay Data
Dale Hattis, Clark University
7 June 2005

Update on International Initiatives for Chemical Specific Adjustment Factors and Physiologically Based Pharmacokinetic (PBPK) Models for Use in Risk Assessment
Bette Meek, Health Canada
1 March 2005

Benchmark-Dose Shopping with Proper Confidence
Walter Piegorsch, University of South Carolina
7 September 2004

Dose-Dependent Transitions in Toxic Mechanisms: Implications for Risk Assessment
David Gaylor, Gaylor and Associates
1 June 2004

Arsenic: Proposed Mechanisms and Risk Assessment Implications
Michael Luster, NIOSH
2 March 2004

Cumulative Risk Assessment for Chemical Mixtures
James Chen, U.S. National Center for Toxicological Research
2 September 2003

Dose-Response Curves in Chemical Carcinogenesis
William Waddell, University of Louisville
3 June 2003

Bystanders, Adaptive Responses and Genomic Instability – Potential Modifiers of Low-Dose Cancer Responses
Julian Preston, U.S. EPA
4 March 2003

Model Uncertainty in Microbial Risk Assessment
Ravi Varadhan, Johns Hopkins University
3 September 2002

Computational Modeling of Mechanisms of Nonmonotonic Dose-Response: Androgen Receptor Activation and Tumor Incidence
Rory Conolly, CIIT Centers for Health Research
4 June 2002

Variability in Dose-Response Assessments
Wout Slob, RIVM
5 March 2002

Dioxin: Dose-Response for Acute Effects
Jim Wilson, Resources for the Future
4 September 2001

Assessment of Risks to Children from Exposure to Environmental Agents
Gary Kimmel, U.S. EPA
Chemical Mixtures Risk Assessment: Current Approaches and Emerging Issues
Peter Robinson, ManTech
Integrating Toxicokinetics and Toxicodynamics in Mechanistic Risk Assessment
Jeff Swartout, U.S. EPA
Risks from Various Exposure Durations
Ron Brown, FDA
4 June 2001

Compound Specific Adjustment Factors – An International Perspective
Bette Meek, Health Canada
3 April 2001

A Model for the Development of Tolerable Upper Intake Levels for Nutrients
Elizabeth Reese; Joseph Rodricks, The Life Science Consultancy
Steve Taylor, University of Nebraska
3 October 2000

Microbial Dose-Response Modeling: Surrogate Dose-Response Models for the Foodborne Pathogen E. coli O157:H7
Peg Coleman, USDA
6 June 2000